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Although many people don’t think it’s ideal, rapé is good for the immune system because of its laxative and expectorant properties. Again, there are different types of rapé, as shamans use different plants to make the powdered mixture. People often feel more grounded during the experience, which allows them to clear up confusion or discomfort about an issue they may have been experiencing. Remember, there is always someone who will do it cheaper, but this is your health and safety we are talking about.

Some researchers have found that the antidepressant benefits of mescaline correlate to a subjects’ willingness to engage with the experience, to face themselves and to act upon the insights received. In one mid-century study, some of the most significant transformations or breakthroughs came about months after the experience itself, even if the initial psychedelic therapy session seemed to be a failure. In the context of psychotherapy, mescaline may also be useful for re-living or recalling repressed memories. Mescaline also activates serotonin and dopamine receptors, which could help boost mood and treat depression. In fact, one of the traditional therapeutic uses for peyote was as an antidepressant, and depression scores are reportedly low among members of the Native American Church, where peyote use is common.

Are there any risks?

The first non-natives to encounter peyote use in the Americas were probably Catholic missionaries and conquistadors during the 16th century. Spanish friar Bernardino de Sahagún, for instance, described a Huichol peyote ceremony held in the desert and estimated that such practices may have been at least 1,980 years old. More recently, with evidence from the Shumla Caves site in Texas, researchers have been able to date ceremonial peyote use to at least 5,700 years ago. It also specifically decriminalizes their cultivation and distribution.

Consuming ayahuasca can thus lead to a hypertensive crisis in those who suffer from these health issues and/or are taking prescription medication to treat them. Other compounds that can interact negatively with ayahuasca’s ingredients include serotonergic agents, such as certain depression medication , some psychoactive substances, and psychostimulants.

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Read more about Rapé here.

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We recognize that some people who identify as women do not have the same anatomy as that depicted in this article. Neural correlates of the psychedelic state as determined by fMRI studies with psilocybin. Kelli Lynn Grey is a professional copywriter and curriculum designer who also writes essays and poems about health equity, education, relationships, and the dynamically changing landscape of drug culture. Her work appears in Inside the Jar, Mashable, and throughout Medium.com.